
More than Lactose: Natural Polymers Revolutionizing Inhaled Drug Delivery
Natural polysaccharides like locust bean gum and chitosan are replacing lactose as safer, more effective carriers for inhaled medications and vaccines.
Showing results for: "inhaled therapeutics" (26 results)

Natural polysaccharides like locust bean gum and chitosan are replacing lactose as safer, more effective carriers for inhaled medications and vaccines.

Inhaled antibiotics deliver drugs directly to lung infections, achieving better results with fewer side effects, which is a game-changer in fighting resistance.

Why is mucus the biggest obstacle to lung drug delivery? Explore the mucosal barrier science reshaping how we design inhaled medicines and vaccines.

Inhalable vaccines trigger powerful mucosal immunity where pathogens enter the body, offering needle-free protection against respiratory diseases.

This architecture is essential for shielding neurons from toxins, pathogens, and fluctuations in the bloodstream, but it also creates a devastating bottleneck for modern medicine. More than 98% of small-molecule drugs and nearly all large biological therapeutics fail to cross the BBB in meaningful amounts, leaving many promising treatments for neurodegenerative disorders, brain tumors, and inflammatory diseases stranded in the circulation.

Alzheimer’s is a progressive neurological disorder with classic clinical symptoms such as dementia, cognitive decline, and behavioural changes, particularly in the ageing population.

Nanotechnology is having a big impact on pharmaceutical sciences, and drug delivery systems are one area where this is most evident. Compared to conventional medication delivery methods, nanoparticles provide a number of benefits, including increased effectiveness and fewer adverse drug reactions.

Biologics have transformed the management of chronic and life-threatening diseases such as cancer, autoimmune disorders, and metabolic conditions. However, their complexity, high production costs, and limited affordability continue to challenge healthcare systems worldwide.

The tumor microenvironment (TME) is a complex and dynamic ecosystem composed of malignant cells, immune infiltrates, stromal elements, and vascular components that collectively influence tumor initiation, progression, immune escape, and therapeutic response. Traditional bulk transcriptomic approaches obscure this complexity by averaging gene expression across heterogeneous cell populations.

Self-healing materials (SHMs) are substances that automatically repair damage, mimicking organic healing. These materials have a wide range of applications, including construction, biomedicine, transportation, and even textiles. SHMs can extend the longevity of manufactured goods and have numerous uses in medical healing (Crawford, 2024).

A future without transplant waitlists? Tissue engineering blends biology and engineering to build living, functional human tissue.

Vancomycin is an essential glycopeptide antibiotic used to treat life-threatening infections caused by Gram-positive bacteria, particularly Methicillin-Resistant Staphylococcus aureus (MRSA). It functions by inhibiting bacterial cell-wall synthesis and is still the most potent drug to be used when others fail (Patel, Preuss, & Bernice, 2023).

Traditionally, Forensic Science relies on Human DNA for contact evidence and individual identification, but limitation arises when the blood cells obtained from the crime scene are degraded or not.

The gut microbiomeover 100 trillion microorganisms, communicates with the brain via the gut–brain axis, influencing mood, cognition, immunity, and stress regulation. Dysbiosis is linked to depression, anxiety, autism spectrum disorders, and neurodegenerative diseases, emphasizing its critical role in mental and neurological health.

Ageing is accompanied by a gradual decline in physiological functions, among which deterioration of the immune system termed immunosenescence—has profound implications for human health.

Today, generalized anxiety disorder is affecting millions of Americans. The disorder usually traps the sufferers in cycles of fear and isolation in a way that even standard treatments cannot relieve completely. UCSF neuroscientist Jennifer Mitchell, PhD, is testing a surprising brand-new approach that can ease symptoms of generalized anxiety disorder by reshaping how the brain thinks and feels.

Title 21 Part 820 of the Code Of Federal Regulations (CFR) details the requirements for the design and production of medical devices. These strict, comprehensive requirements are in place for good reason, we want these devices to work.

Healthcare is changing faster than ever before. Thanks to breakthroughs in artificial intelligence (AI), genomics, and wearable technology, medicine is entering the era of smart health, where data, devices, and biology work together to create care tailored to the individual.

Animal models have traditionally served as the cornerstone of drug safety evaluation; however, major translational challenges persist due to interspecies differences in physiology, metabolism, and genetic regulation. Many compounds demonstrating favorable toxicity profiles in animals later fail during human trials or are withdrawn post-marketing due to unforeseen adverse effects, especially hepatotoxicity and cardiotoxicity (Lee et al., 2025).

Discover how antigen-presenting cells like dendritic cells and macrophages are being recruited through smart particle design for vaccines and immunotherapy.