
Atherosclerosis and its Role in the Immune System
Learn how the leading cause of death worldwide activates the immune system and how making a few lifestyle changes can decrease your risk of severe chronic disease.
Showing results for: "immunity" (24 results)

Learn how the leading cause of death worldwide activates the immune system and how making a few lifestyle changes can decrease your risk of severe chronic disease.

Discover how antigen-presenting cells like dendritic cells and macrophages are being recruited through smart particle design for vaccines and immunotherapy.

Ageing is accompanied by a gradual decline in physiological functions, among which deterioration of the immune system termed immunosenescence—has profound implications for human health.

The tumor microenvironment (TME) is a complex and dynamic ecosystem composed of malignant cells, immune infiltrates, stromal elements, and vascular components that collectively influence tumor initiation, progression, immune escape, and therapeutic response. Traditional bulk transcriptomic approaches obscure this complexity by averaging gene expression across heterogeneous cell populations.

Inhalable vaccines trigger powerful mucosal immunity where pathogens enter the body, offering needle-free protection against respiratory diseases.

In Sci-fi visions of distant futures, some imagine sprawling intergalactic civilizations. Scaffolds built around stars harvesting their energy. Fusion reactors, cyborgs, superintelligent implants. But the future of artificial bones, though perhaps more mundane, could be a life saving science.

Cell and gene therapies represent a seismic shift in healthcare. They promise to cure the incurable, restoring sight to the blind and erasing cancer from the blood. But this frontier is wild. It comes with biological price tags, potential genetic misfires, and a regulatory landscape that is still being mapped.

Vaccines need precise temperature control to work but maintaining the cold chain wastes half of all doses globally. New thermostable formulations could change everything.

Why is mucus the biggest obstacle to lung drug delivery? Explore the mucosal barrier science reshaping how we design inhaled medicines and vaccines.

Modern healthcare is undergoing a silent revolution. Now to treat a disease in the healthcare system, there is no longer a need to wait for symptoms to appear.

Wound healing is a complex and dynamic biological process that occurs through four overlapping phases: hemostasis, inflammation, proliferation, and maturation. To repair tissue damage, the body works intensively, thereby significantly increasing cellular metabolic demands.

Inhaled antibiotics deliver drugs directly to lung infections, achieving better results with fewer side effects, which is a game-changer in fighting resistance.

Natural polysaccharides like locust bean gum and chitosan are replacing lactose as safer, more effective carriers for inhaled medications and vaccines.

The gut microbiomeover 100 trillion microorganisms, communicates with the brain via the gut–brain axis, influencing mood, cognition, immunity, and stress regulation. Dysbiosis is linked to depression, anxiety, autism spectrum disorders, and neurodegenerative diseases, emphasizing its critical role in mental and neurological health.

Animal models have traditionally served as the cornerstone of drug safety evaluation; however, major translational challenges persist due to interspecies differences in physiology, metabolism, and genetic regulation. Many compounds demonstrating favorable toxicity profiles in animals later fail during human trials or are withdrawn post-marketing due to unforeseen adverse effects, especially hepatotoxicity and cardiotoxicity (Lee et al., 2025).

In this study, I explore how cancer risk is distributed across the animal kingdom, emphasizing the role of life-history traits, reproductive strategies, and social behavior in shaping susceptibility to disease. Drawing on recent findings in comparative oncology, the article examines patterns that challenge traditional assumptions, such as the relationship between body size and cancer, and highlights evolutionary mechanisms that may confer resistance in certain species.

Tuberculosis (TB) remains one of the world's deadliest infectious diseases, claiming over a million lives each year. TB is the deadliest infectious disease known today, claiming more lives than COVID-19. TB is caused by the bacterium Mycobacterium tuberculosis. TB spreads through the air when infected people breathe, cough, sneeze,

This architecture is essential for shielding neurons from toxins, pathogens, and fluctuations in the bloodstream, but it also creates a devastating bottleneck for modern medicine. More than 98% of small-molecule drugs and nearly all large biological therapeutics fail to cross the BBB in meaningful amounts, leaving many promising treatments for neurodegenerative disorders, brain tumors, and inflammatory diseases stranded in the circulation.

As a pharmacist during clinical clerking, I frequently encounter patients who use the term “toilet infections” to describe symptoms that clinically align with bacterial vaginosis, urinary tract infections, or yeast infections. This widespread misconception often stems from the assumption that symptoms occurring after the use of public toilets must be caused by them.

Can algorithms predict sickness before you feel it? Explore how AI is using smartwatch data and ECGs to detect diseases like Alzheimer's and AFib early.